Synthace Combines ChatGPT And Digital Experiments In First Step Toward A True AI Scientist

Synthace, creators of the world’s first digital experiment platform for life science R&D, announces the successful integration of their platform with OpenAI’s ChatGPT. This revolutionary development lets scientists use a natural language interface to describe their intent, use the AI to design complex experiments, and then run those experiments on lab equipment.

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“The reason we’ve been able to pull this off is because of the advanced digital experiment model that underpins our platform. Our proprietary technology builds a detailed model of every single liquid and machine movement that happens in the lab. ”

At a glance: what Synthace has done, and why it matters

The connection between ChatGPT and Synthace brings the power of generative AI to biology experiments themselves. Scientists can describe complex experiments they would like to run with simple natural language prompts, then work with the AI to define the details and specifications of their experiment.

Experiment design and lab automation are difficult and time-consuming processes in life science research and development. This breakthrough drastically reduces the time and effort needed for both of these things, meaning scientists can spend more time on creative problem-solving.

Once adopted widely, this will have a revolutionary impact on the ability of scientists to make breakthroughs in all areas of the life sciences, including drug discovery, therapeutics, food tech, climate tech, agritech—and beyond.

A turning point for the power of scientists in the lab

Guy Levy-Yurista PhD, Synthace CEO, said “This is a truly incredible achievement, and a significant development in our mission to help scientists unlock the full power of biology.

Augmented and empowered by AI, any scientist with access to this technology will be able to perform far more experiments at a greater level of power and complexity than would have been possible before.

This isn’t the first time biology has benefitted from artificial intelligence, but this is the first time a scientist can use it to design and run their experiments in the lab at an unprecedented speed.

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What used to seem like science fiction is now here, and with it we believe we will see a revolution of new possibilities in the coming years. This is a truly defining moment for the life sciences, and one we’re proud to be a part of.”

How it works: Synthace integration with AI and lab equipment

Using simple prompts, a scientist can describe and specify the details of an experiment in conversation with ChatGPT, including how it should run in a laboratory and on what equipment. In the above video, ChatGPT helps a Synthace scientist develop a growth medium for CAR T Cells, which can be used to engineer immune cells to treat cancer. As a first step it provides a list of ingredients, followed by the detailed definition of an experiment that will help find the statistically optimal combination.

With the experiment defined, it’s then transferred over to the Synthace platform to simulate and then execute the experiment in the lab (in the video, a Tecan Fluent liquid handler). With a single additional prompt, the same experiment can be converted to run at a smaller scale on an entirely different piece of equipment (an SPT Labtech Dragonfly dispenser), giving the scientist complete freedom to design and run their experiment on their platform of choice.

The Synthace platform contains its own sophisticated machine-learning technology that understands and predicts the ways in which different liquids behave and are handled in the lab. Integrated together with OpenAI’s ChatGPT, the two communicate together as the scientist describes their protocol, problem-solving any potential errors and refining the machine code to ensure it will work on the selected machine.

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