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Bruker Introduces Fast BioAFM For Automated Mechanobiology

Novel, high-performance JPK NanoWizard V enables new dynamic mechanobiology research capabilities with option for seamless optical microscope integration

Bruker announced the release of the JPK NanoWizard V BioAFM, a novel system that marks a milestone in automation and ease of use for life science atomic force microscopy research. NanoWizard V is a very fast, automated BioAFM that can optionally be fully integrated with advanced optical microscopes. It enables rapid, quantitative mechanical measurements and the analysis of dynamics on samples ranging in size from sub-molecular to cells and tissues. The automated setup, alignment and re-adjustment of system parameters opens new possibilities for long-term, self-regulating experiments on mechanobiological dynamics.


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“The system’s promised speed and resolution, ease of use, and up-to-millimeter-range capabilities make this a game changer for AFM investigations in nanomedicine and biomedical applications,” said Dr. David Martinez Martin, Senior Lecturer in Biomedical Engineering and Co-Chair of the Sensors and Diagnostics Cluster of the Nanohealth Network at the University of Sydney, Australia. The focus of Dr. Martinez Martin’s research is on the discovery of new biomarkers for health and disease, and cell physiology.

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“We believe that the NanoWizard V is the most advanced BioAFM, and it combines three significant innovations in one system: rapid, quantitative mechanobiology measurements, fast scanning AFM, and automation that requires minimal user input,” added Dr. Heiko Haschke, Bruker’s Director of BioAFM. “Over the last decade, we have gathered a wealth of experience in quantitative nanomechanics using the PeakForce Tapping® and Quantitative Imaging (QI) modes. By uniting the best aspects of both in our new PeakForce-QITM mode, we empower novices and experts alike to perform high-resolution, quantitative mechanobiology BioAFM experiments. We expect this new system to significantly contribute to a more comprehensive understanding of dynamic cellular processes and correlated molecular mechanisms.”

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