Molecular Devices Launches Next-Gen Monoclonal Verification Imaging Platform For Automatic, Day zero Monoclonality Assurance

CloneSelect® Imager FL provides a seamless end-to-end workflow for: High-speed label-free and multi-channel fluorescence full-well image acquisition, Intelligent data analysis, Monoclonality report generation

Molecular Devices, LLC., a leading provider of high-performance life science solutions, has officially launched its CloneSelect Imager FL platform (CSI FL). The CSI FL is capable of imaging and reporting on label-free and multiplexed gene-edited single cells with automated monoclonal verification reporting.

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“Label-free, gene-edited monoclonal imaging techniques can be a time-consuming and highly-subjective process,” said Dan O’Connor, Vice President, Drug Discovery, Molecular Devices. “By using multi-channel fluorescence, the CSI FL provides complete assurance that clonal cell lines for mAb production, drug screening, and cell and gene therapies came from a single gene-edited progenitor. The CSI FL offers high-speed imaging of banked cell lines with CRISPR-confirmed edits, helping to expedite the therapeutic discovery process while providing full audit trail regulatory reporting.”

By leveraging Molecular Devices’ existing label-free, best-in-class, clone imaging technology, the CSI FL adds the capability of imaging sensitive green and red fluorescent proteins to deliver:

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• Publication-ready, high-resolution imaging and analysis due to accurate cell detection regardless of cell type and condition, providing automatic confluence analysis and monoclonality assurance
• Industry-leading acquisition times for rapid single cell confirmation, verifying and tracking monoclonality from day zero
• Demonstrated IND success with an automated and customizable Monoclonality Report feature that streamlines creation of supporting documentation for regulatory agencies

“Our customers are as diverse as their scientific research, ranging from cell line development, to 3D biology, to drug screening – yet they’re united in a desire to work more efficiently, and with technologies that uncover answers, faster,” said Susan Murphy, President of Molecular Devices. “The CSI FL joins a robust product portfolio designed to help organizations move forward in their drug discovery journey with speed, accuracy, and confidence.”

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